The Relevance Of Clodronate Liposome In Medical Science

By Roxanne Cruz


Perhaps medical science is the best industry in science because of the it made possible the inventions and discoveries that was once only imagined. Different solutions were found to cure different diseases acquired from viruses and bacteria. For example, thousands of residents died because yellow fever has got no medicine. But overtime, because of these hard working discoverers, vaccine for the fever was invented. Clodronate liposome is surely one of discoveries that is going to play a significant role in medicine industry.

Clodronate also known as clodronate disodium and clodronic acid is a first generation non nitrogenous bisphosphonate. It is a drug scientifically approved, tested, and used to prevent and treat the cases of osteoporosis especially to the women who have reached the post menopausal period. It is also used in the experimental medicine to deplete macrophages.

These are white blood cells within tissues. Macrophages are produced by the division of the white blood cells formed in the bone marrow and spleen. These kind of white blood cell is known to be as monocytes which ingest foreign particles after it was formed. Basically, macrophage is the core of the system which fight against infectious viruses and diseases.

Liposomes are the microscopic bubbles which are consist of fatty liquids. These are used in cell biology to study the cell and find cures to any diseases found in the cell. They are drugs that are used to help treat and cure cancer. But it does not only limit to cancer, scientists also approved that these drugs can be used in curing other diseases. It is made of liquid and phospholipids.

Medical science discovered clodronate liposome that will function in the suppression of macrophages. It is known to be the fighter against microorganism. Aside from defending the body from the organisms that will infect and impair the system, it can also be the source of the disease.

In natural circumstances, the healthy immune system will cope diseases up like coughs and colds. In the contrary, the damaged system will attack every cells it will eat each particles, both the healthy and damaged. When this doom happens, severe illnesses will take place affecting the body from functioning well.

Immune response does protect the body from invasion of the infectious organisms. But damages will also happen in the body when the transplant was rejected leading to the autoimmune condition. Transplant rejection is the side effect of the immune response. When a new organ is placed on the patient, cells will automatically work against forcefully to the organ cells. It will soon result to transplant rejection.

Because of these cases that will damage the body defense against harmful organisms, doctors and scientists fumbled upon the discovery of liposome. This medicine is made of bisphosphonate that will help lessen the quantity of macrophage. As soon as macrophage detects that this drug transported inside the body is foreign, it will automatically engulf it whole through phagocytosis.

This discovery marked a significance in the history of medicine industry. Not only that the cancers will be treated, other diseases will be as well. However, even though clodronate liposome is reported to help treat cancer and many other illnesses, consult your own doctor first. This is to ensure your health will not be at risk. Ask prescriptions from your doctor if you could have one.




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